三阴交穴位针刺对2型糖尿病患者血糖水平和心血管功能的影响：一项随机安慰剂对照研究

doi:10.1016/j.dcmed.2024.12.002

三阴交穴位针刺对2型糖尿病患者血糖水平和心血管功能的影响：一项随机安慰剂对照研究

Effects of needling at Sanyinjiao (SP6) acupuncture point on blood glucose levels and cardiovascular functions in patients with type 2 diabetes mellitus: a randomized placebo-controlled study

摘要

摘要:
目的本研究旨在确定三阴交（SP6）穴位针刺对2型糖尿病患者（T2DM）随机血糖（RBG）水平和心血管功能的影响。
方法在这项随机安慰剂对照研究中，期间从印度金奈政府瑜伽和自然疗法医学院和医院招募T2DM患者（年龄35 − 65岁），时间跨度为2022年1月5日至2023年3月15日。参与者被随机分配到针灸组或假针灸组。针灸组接受双侧三阴交（SP6）穴位针刺，而假针灸组接受非穴位点（距三阴交侧位1.5寸处）针刺，每次30分钟。主要观察指标为RBG，次要观察指标包括收缩压（SBP）、舒张压（DBP）、脉搏率（PR）、脉压（PP）、平均动脉压（MAP）、心率血压乘积（RPP）和心率血压双乘积（Do-P）。所有参数在干预前后立即进行评估。
结果共有100名T2DM患者参与研究，被随机分配至针灸组（n = 50）和假针灸组（n = 50）。组间分析显示，针灸组与假针灸组相比，RBG（P < 0.001）、SBP（P = 0.035）、DBP（P = 0.008）和MAP（P = 0.009）显著降低。组内分析显示，针灸组RBG（P < 0.001）、SBP（P < 0.001）、DBP（P = 0.008）、PP（P = 0.023）、MAP（P < 0.001）、RPP（P < 0.001）和Do-P（P = 0.002）显著降低，而假针灸组仅在脉搏率（PR）上表现出显著降低（P = 0.023）。
结论与非穴位点针刺相比，30分钟的三阴交（SP6）穴位针刺可以降低T2DM患者的RBG并改善其心血管功能。三阴交（SP6）穴位针刺可能作为一种即时、非药物干预手段，加强T2DM患者的血糖控制管理和促进心血管健康。

Abstract:
Objective To determine the effect of needling at Sanyinjiao (SP6) on random blood glucose (RBG) levels and cardiovascular function in patients with type 2 diabetes mellitus (T2DM).
Methods In this randomized placebo-controlled study, T2DM patients (aged 35 – 65 years) were recruited from the Government Yoga and Naturopathy Medical College and Hospital, Chennai, India, between January 5, 2022 and March 15, 2023. Participants were randomly assigned to either acupuncture group or sham acupuncture group. The acupuncture group received bilateral needling at Sanyinjiao (SP6) while sham acupuncture group received needling at a non-acupuncture point 1.5 cun lateral to Sanyinjiao (SP6) for 30 min. Primary outcome was RBG, and secondary outcomes included systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse rate (PR), pulse pressure (PP), mean arterial pressure (MAP), rate pressure product (RPP), and double product (Do-P). All parameters were assessed immediately before and after intervention.
Results A total of 100 patients with T2DM were enrolled in the study, and blinded to acupuncture group (n = 50) and sham acupuncture group (n = 50). Intergroup analysis showed that significant reductions in RBG (P < 0.001), SBP (P = 0.035), DBP (P = 0.008), and MAP (P = 0.009) were found in acupuncture group compared with sham acupuncture group. Within-group analysis showed significant reductions in RBG (P < 0.001), SBP (P < 0.001), DBP (P = 0.008), PP (P = 0.023), MAP (P < 0.001), RPP (P < 0.001), and Do-P (P = 0.002) in acupuncture group, whereas sham acupuncture group showed a significant decrease in PR (P = 0.023) only in the post-test assessment compared with pre-test assessment.
Conclusion A period of 30 min of needling at the Sanyinjiao (SP6) acupuncture point reduces RBG and promotes cardiovascular function in patients with T2DM as compared with needling at non-acupuncture points. Sanyinjiao (SP6) acupuncture may offer an immediate, non-pharmacological intervention to strengthen glycemic control management and cardiovascular health in T2DM patients.

HTML全文

参考文献(21)

施引文献

资源附件(0)